Dementia and COVID-19: a conjunction of challenges

The complexities of preventing and managing infection are multiplied in people living with dementia. Problems with memory and understanding limit self-care, while the proximity of carers pose additional risks. In patients who become critically ill, delirium may exacerbate dementia.

In the UK, 1 in 6 people with dementia are over 80 years old.1 The mean age at onset of motor symptoms of Parkinson’s disease (PD) is around sixty years.2 Unexpectedly, the number of comorbidities rises steeply with age, with 45.7% of people aged 65 and over suffering with two or more comorbidities.3

So it is clear that people with these forms of neurodegenerative disease – and especially those with dementia – have a high age-related risk of developing complications from COVID-19 infection, and hence a high risk of hospitalisation and need for intensive care.

 

Double hit

With 50 million people in the world having dementia,4 and with the global total of known COVID-19 cases rocketing to over 5.5million on a rapidly accelerating curve,5 we have an unfortunate conjunction of challenges.

Wang et al6 have recently given the situation a sober appraisal. Their letter to The Lancet identified many factors that pose particular problems for people with dementia, including those that don’t reside in a nursing home:

  • Limited access to and understanding of scientific information
  • Memory problems making it difficult to maintain social distance and other protective measures such as handwashing
  • Little or no capacity to use the internet and social media
  • Reliance on one or more carers and the inevitability of intimate contact
  • For those very ill who need hospital care, there is the stress of displacement and the risk of hypoxia-induced delirium

Although to a lesser extent, similar considerations apply to elderly people with advanced PD. Lack of contact with physiotherapists and the inability to take recommended outdoor exercise are specific problems.

 

Sources of support

Recent experience in China suggests the importance of multidisciplinary working, of making counselling available to carers, and of the remote delivery of stress reduction programmes such as relaxation and meditation.6

Resources to help cope with the COVID-19 emergency have been developed by the American Academy of Neurology.7 These cover recommendations on the implementation of telemedicine, including how to perform a remote neurological exam. There is specific advice on telemedicine for PD, and a live demonstration.8

References
  1. Alzheimer’s association: 2018 Facts and Figures. Available at https://www.alzheimers.org.uk/about-us/news-and-media/facts-media [Accessed May 2020]
  2. Peretz C, et al. Parkinsonism and Related Disorders 2014;20:69-74
  3. Kingston A, et al. Age and Ageing 2018;47:374-380
  4. https://www.who.int/news-room/fact-sheets/detail/dementia [Accessed May 2020]
  5. COVID-19 Dashboard at John Hopkins University (JHU). Available at : https://www.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf6 [Accessed May 2020]
  6. Wang H, et al. Lancet 2020; March 30. https://doi.org/10.1016/S0140-6736(20)30755-8 [Accessed May 2020]
  7. https://www.aan.com/tools-and-resources/covid-19-neurology-resource-center/ [Accessed May 2020]
  8. https://www.aan.com/tools-and-resources/practicing-neurologists-administrators/telemedicine-and-remote-care/ [Accessed May 2020]
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